Susan Perl worked as an illustrator at Condé Nast for Vogue, House & Garden and Glamor until 1952. After a stay at the CG Jung Institute in Zurich from 1952 to 1954, she became a freelance illustrator in the USA. She lived in Manhattan .
Perl also worked for advertising and product design. From 1966, her drawings accompanied a PR campaign by the children's clothing manufacturer Healthtex under the title The Handy Answers to Hard Questions Asked by Children in the Health-tex Years .
She has drawn for the magazines Harper's Bazar, Reader's Digest, Columbia Pictures , LIFE and for the children's page in The New York Times Sunday Magazine. She was particularly known for her children's and animal motifs and illustrated a large number of books, including some of her own children's books and also her own comic The Sex Life of the American Female.
